It was at that moment the penny dropped: Larry (whose voice I interpreted as a painful combination of David Niven and Frankie Howerd) was the future Lawrence, the impenetrable darling of the moderately intellectual Boston set.
Getting rid of that structural deficit will require a painful combination of spending cuts and tax increases.The Treasury estimated in December that fiscal retrenchment building up to more than 5% of GDP would be needed to fill the hole.
Still, what we have here is a painful combination: her sense that she was without beauty, her sense that she could not make the kind of ballets she most valued, her sense that what she did was just a substitute for something else, something more longed-for, which, inexplicably, other people had and she didn't.
But the voice of the chief scientist, Prof Martin Siegert, conveys the painful combination of exhaustion and failure that marks all projects that go wrong.
Everything good I've gotten in life, I've gotten from a painful combination of working hard and being uncomfortable.
Companies in the Energy and Materials sectors are also negatively affected by the painful combination of slower Chinese economic growth and sharply lower commodity prices.
Tomorrow morning, the state of Ohio will give a special pillow to a sick man, so that he will ostensibly be more comfortable as they kill him with an untested, potentially extremely painful, combination of drugs.
Search terms used were: "HIV" "AIDS" "pain" "painful" "neuropathy" "neuropathic", in combination with "random" "randomised" and "double-blinded".
This subgroup is characterized by a combination of severe painful attacks and pressure induced pain whereas spontaneous pain, allodynia and thermal hyperalgesia are only mildly present.
The COMBO-DN study that has just been completed (81) is the largest combination trial in painful DSPN and assessed whether combining standard doses of duloxetine and pregabalin is superior to increasing each drug to its maximum recommended dose in patients with incomplete pain relief.
