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An accelerated ACS rule-out process integrating ECG, score-based risk assessment and biomarker assays was first proposed by Than et al. in the Asia-Pacific Evaluation of Chest Pain Trial (ASPECT) study [8].
A cervical pain trial meta-analysis studying manual therapy [61] found that manipulation (high velocity low amplitude) and mobilization produce similar effects on pain and are not better at short- and intermediate-term than controls for pain relief.
Section 6 returns to the analysis of the dental pain trial.
This trial is officially called the Maastricht Ultrasound Shoulder pain Trial (MUST).
I created a hypothetical pain trial with patients divided evenly between a treatment and a control group.
This method is applicable to the dental pain trial but does not extend easily to a more general regression situation.
Similar(42)
After 50 years, the reporting of results from acute pain trials warrants a fresh look.
Notably, a range of potential biases hinders the interpretation of chronic pain trials.
The hypothesis was that local treatment with granisetron would be superior to isotonic saline (control-substance) regarding the outcome domains recommended for pain trials by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) [24, 25].
An IMMPACT consensus meeting was therefore convened to identify the critical research design considerations for confirmatory chronic pain trials and to make recommendations for their conduct.
Therefore, an Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials consensus meeting was convened in which the assay sensitivity of chronic pain trials was reviewed and discussed.
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