Sentence examples for pain target from inspiring English sources

Implantable stimulators, which can be an effective treatment for pain, target the circuit with small jolts of electricity.

If CGRP fulfills its promise as a blockbuster pain target, that success could signal to drug developers that effective treatments for other complex and seemingly intractable pain disorders, such as fibromyalgia, are also within reach, Moskowitz says.

Of the 82 patients with abdominal pain, target pancreatic stones were successfully removed from 64.

Cav2.2 (N-type) has been identified as a valid pain target that can be inhibited by the selective blocker ziconotide to relieve chronic pain.

However, from our knowledge of the pathogenesis of pain, targeting local chronic inflammation and fibrotic processes closely related to painful symptoms might still be relevant for managing this condition.

Many new analgesic drug candidates believed to act on scientifically relevant pain targets have failed to show efficacy in clinical trials.

These typically target specific sodium channels with the greatest validation as pain targets, and are designed to engage modes of inhibition, or compartment localization, aimed at delivering an improved safety profile.

Current treatments for low back pain targeted at the IVD fall into three categories: symptomatic remedies (analgesics, bed rest, and muscle-strengthening exercises); minimally invasive surgery (microdiscectomy and foraminotomy; major surgery (spinal fusion and disc replacement).

AAV for pain targeting the peripheral nervous system was proven to be efficacious in rodent models several years ago, but has not yet been tested in humans.

Recent models of bone cancer pain, targeting the femurs in mice, consisted in arthrotomia, displacement of the patellar ligament and knee joint alteration [24], [30].

> -wrap-foot> In order to corroborate the subjective nature of the pain thresholding procedure, we performed an ANOVA on the unpleasantness ratings for low and high pain stimulation during the self and the other conditions with two within-subjects factors (Pain: pain versus no-pain; Target: self versus other) and one between-subjects factor (Group: autism spectrum condition versus control).