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The GCPS was used to classify individuals according to the chronic pain grades: I = low pain intensity and low levels of pain-related disability, II = high pain intensity and low levels of pain-related disability, III = moderate pain-related disability and IV = severe pain-related disability.
Treatment-related tumour pain (Grades 1 3) was reported in 12 patients (26%) at doses of 40.8 mg m−2 and above.
Comparisons were made across Chronic Pain Grades (I, II, III, and IV) using one-way Analysis of Variance (ANOVA) for continuous variables and chi-square tests for categorical variables.
The pain grades show a statistically significant and monotonically increasing relationship with employment status (full employment to unemployment), amount of pain-related functional limitation, increasing levels of depression, and decreasing levels of self-rated health [ 23, 24].
Some authors have attempted to describe phases in the course of back pain; these range from the biomedical 'ageing' processes described by Laurens Rowe in 1983 [ 92], to the widely used Chronic Pain Grades characterized by Von Korff et al. [ 93], the stages of back pain described by Raspe et al. [ 62], and more recently an ordering of back pain trajectories suggested by Dunn et al. [ 36].
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The intensities of other AEs, including unsolicited AEs were graded as follows: Grade 1, "easily tolerated" ("painful on touch" for injection site pain); Grade 2, "interferes with normal activity" (or "painful when limb is moved" for injection site pain); and Grade 3, "prevents normal activity" (or "considerable pain at rest" for injection site pain).
cGrade 1, "easily tolerated" ("painful on touch" for injection site pain); Grade 2, "interferes with normal activity" (or "painful when limb is moved" for injection site pain); and Grade 3, "prevents normal activity" (or "considerable pain at rest" for injection site pain).
The Chronic Pain Grade is a multi-dimensional tool, measuring persistence, intensity and duration of painful conditions.
For the definition of recurrence, migraine pain was rated as follows: grade 0, no pain; grade 1, mild pain; grade 2, moderate pain; grade 3, severe pain.
3) Chronic pain grade (CPG) The chronic pain grade classification was termed as following and using previously calculated CPI and DP (Table 2).
Main Outcome Measures: Chronic Pain Grade questionnaire, Short-Form McGill Pain Questionnaire, pain sites, and treatments.
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