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LCSS Gelibter A et al. (2005) [20] "Compassionate-Use" NSCLC III/IV Gefitinib primary Improvements in fatigue, insomnia, and pain, deterioration in sore mouth, chest-pain, diarrhea.
At the late measurement women exhibited pain (EQ-5D pain/discomfort and SF-36 Bodily Pain), deterioration in Physical Functioning (SF-36 PF) and overall SF-36 Physical Component Scale (PCS).
First, the scores of all questionnaires were influenced by musculoskeletal diseases, which are conditions characterised by physical pain, difficulty of movements, immobility and, often, partly because of the associated pain, deterioration in daily activities, and which, therefore, could have an effect also on vitality and social life.
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The disease can cause vastly enlarged livers and spleens, anemia, low platelet counts, and bone pain and deterioration.
I do say that I find it incompatible with my conception of God that a patient be effectively tortured by being kept alive with no hope of anything but pain and deterioration.
And while his lyrics are still awash in thoughts of pain and deterioration — "There's nothing much left of me," he sings in "Dream Captain" — he also lashes out at those who wronged him and hangs tough.
It is a source of pain and deterioration of joint function, with important socioeconomic consequences.
People continued to mention the incurability of knee pain, thought deterioration was likely and that surgery was still considered the most effective way to improve pain and function.
Physician-rated pain indicated deterioration at the beginning of cycles 3 (n=16, median change=−1, P=0.04) and 4 (n=9, median change=−1, P=0.03), when compared to baseline (n=25, median=2).
On the basis of reports in the literature and our earlier trial (VenUS I), 4 we established a list of possible treatment related adverse events a priori (pressure damage, maceration, excoriation and infection ulcer related pain, ulcer deterioration).
A vast majority of patients with rheumatoid arthritis (RA) experience pain, functional deterioration, rigidity and work disability due to atrophy and irreversible joint destruction if not treated efficiently and early.
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CEO of Professional Science Editing for Scientists @ prosciediting.com