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One patient was given paclitaxel instead of assigned EoP and was excluded from response evaluation.
The main criticism of our study would be the decision to use paclitaxel instead of docetaxel as second-line chemotherapy.
Our modified regimen, such as "weekly paclitaxel instead of tri-weekly or tri-weekly docetaxel", also achieved a pCR rate of 65.1%%.
What is the additional cost of prescribing 305 mg of paclitaxel instead of 300 mg? Consideration should be given to using a range of 'fixed doses' for a particular drug that could be used as the starting dose and for dose adjustments.
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In cost-effectiveness terms, the probability of making the wrong decision by recommending nab-paclitaxel instead of conventional paclitaxel is given by the complement of the probability of being cost-effective.
In pretreated patients who received nab-paclitaxel instead of conventional paclitaxel, the difference in overall survival (OS) was statistically significant (56.4 versus 46.7 weeks, respectively; HR = 0.73; P = 0.024).
The same research group did a later study that was similar to the first but which employed paclitaxel (Ptx) instead of doxorubicin, and the insonation parameters were slightly different [ 9].
The nanoparticles were suspended in thiolated chitosan solution at a concentration of 9.5 mg/ml by sonication at 30 W power output for 30 s in an ice bath, and then were collected by centrifugation at 80,000×g for 15 min. The coumarin-6-loaded nanoparticles were prepared by encapsulation of 0.1% (w/v) coumarin-6 instead of paclitaxel.
They believed that docetaxel instead of paclitaxel decreased neurotoxicity.
We will use chemoresistant or chemosensitive instead of paclitaxel resistant and sensitive for EOC patients.
The fact that we administered paclitaxel over 3 h instead of 24 h might explain this difference (Eisenhauer et al, 1994).
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CEO of Professional Science Editing for Scientists @ prosciediting.com