Sentence examples for paclitaxel compared to from inspiring English sources
2780 AD is about 2,000-fold 2,000-foldto paclitaxel comparesistante parentol A2780 cell line.
As expected, HEK-MRP7-2 cells released a significantly higher percentage of accumulated paclitaxel compared to HEK293-pcDNA3.1 cells, and the amount of paclitaxel that was effluxed increased with time.
Studies show that this formulation increases the therapeutic efficacy of paclitaxel compared to its conventional formulation.
Figure 2 A documents that NeuTL spheres are more resistant to doxorubicin and paclitaxel compared to their adherent counterparts, consistent with their TIC nature.
Recently, the superior therapeutic index of weekly paclitaxel compared to the triweekly schedule has been demonstrated in gastric cancer patients (Ohtsu et al, 1998; Yamada et al, 2001; Kakeji et al, 2005).
When cell death was analyzed by FACS, we found that breast cancer cells exposed to fractionated radiation showed more resistance to cisplatin, etoposide, and paclitaxel compared to non-irradiated cells (Fig. 5a c).
We have now designed a randomized phase 3 intergroup study (J-AXEL, UMIN000017487) to examine the clinical benefit and safety of nab-paclitaxel compared to docetaxel in patients with previously treated advanced NSCLC.
The concentration at which proliferation of K1735-M1 cells was inhibited by 50% (IC50) was 0.1 µM with AMF/PGI-paclitaxel compared to 1 µM for free paclitaxel (p<0.001; Figure 6A, left panel).
Preclinical studies in animals demonstrated lower toxicities for nab-paclitaxel, with the maximum-tolerated dose (MTD) approximately 50%% higher for nab-paclitaxel compared to paclitaxel [ 9].
A higher rate of maculo-papular rash occurred in Chinese breast cancer patients treated with weekly nab-paclitaxel compared to western patients.
PEGPH20 is currently being assessed in a randomized Phase 2 clinical trial assessing its efficacy as a first-line therapy against metastatic pancreatic cancer in combination with gemcitabine/nab-paclitaxel compared to gemcitabine/nab-paclitaxel alone (https://clinicaltrials.gov/ct2/show/NCT01839487).gov/ct2/show/NCT01839487
