Sentence examples for paclitaxel at a from inspiring English sources

Both nanoparticles successfully entrapped paclitaxel at a final concentration of 150 μg/ml (over 6% drug loading) with particle sizes less than 200 nm and over 85% of entrapment efficiency.

METHODS: Adults age > 18 years with refractory or recurrent, aggressive NHL who were not considered curable with standard high-dose therapy received paclitaxel at a dose of 80 mg/m2 weekly for 5 weeks for 2 cycles.

In the present study, our intention was to conduct a phase I study by escalating the dosage of irinotecan while keeping paclitaxel at a standard dose.

The majority of patients were given AC followed by paclitaxel at a dose of 175 mg/m2 for 4 cycles adminitered at 2- or 3-week intertreatment intervals.

Among 474 women randomly assigned to paclitaxel at a dose of 175, 210, or 250 mg/m, adequate primary tumor tissue was available from 175.

If considered in their best interest, patients continued on a 3-weekly schedule of i.v. paclitaxel at a dose of 175 mg m−2.

Another phase 1 GOG pilot study administered weekly IP paclitaxel at an initial dose of 20 mg/m for 16 weeks to 33 patients and found that IP paclitaxel at this dose was feasible and well tolerated.

This randomised, open-label, phase II study tested the addition of ASA404 1200 mg m−2 to a standard therapy regimen comprising carboplatin dosed to area under the plasma concentration time curve (AUC) 6 mg ml−1 min plus paclitaxel at an FDA-approved dose of 175 mg m−2.

Subsequently, cells were suspended in the medium containing [3H]-paclitaxel at a concentration of 0.1 µM with or without the TKIs nilotinib and imatinib (5 µM) for 1 h at 37°C.

Mice were treated with nab-paclitaxel at a final concentration of 50 mg kg 1 paclitaxel I.V. once a week and gemcitabine at a final concentration of 50 mg kg 1 I.P. twice a week for 3 weeks.

In a pivotal phase III trial of patients with MBC, nab-paclitaxel at a slightly lower dose of 260 mg/m demonstrated superior antitumor activity compared with sb-paclitaxel 175 mg/m (both administered q3w) [ 20].