Sentence examples for package and gene from inspiring English sources

Gene expression analysis was performed at all three timepoints to identify early gene signatures predictive of the magnitude of the subsequent adaptive T cell response using the significance analysis of microarrays (SAM) statistical package and gene set enrichment analysis.

Data were normalized with the variance stabilization transformation algorithm (Bioconductor vsn package) and genes with significant change (P < 0.05, log-fold-change > 0.5) were recorded.

Histone modifications are essential in regulating chromatin packaging and gene expression for proper development and cell function.

Core histone proteins are a highly evolutionary conserved basic structural unit of chromatin with roles in DNA packaging and gene expression, however, it has been suggested that different cell types possess unique combinations of these histone proteins [62], [63].

More than two dozens of site-specific histone modifications have been described [13], [14], and the acetylation and methylation of lysine residues in the tails of nucleosomal histones have been shown to exert crucial influences on chromatin packaging and gene expression [15], [16].

Changes in histone modifications directly affect chromatin packaging and gene expression [ 30].

HP1γ is a member of the HPI family of proteins involved in chromatin packaging and gene regulation.

Modifications of the N-terminal tails of histone proteins play a crucial role in chromatin packaging and gene expression.

The genomics resources (e.g., improved assemblies, gene annotations, genome browsers) produced in this study provide a foundation for future investigations into the factors that impact chromatin packaging and gene expression in a heterochromatic domain.

CBX3 has been reported to function in chromatin packaging and gene expression regulation and has also been found to possibly regulate euchromatin repression by associating with nucleosomes in heterochromatin [ 113].

Results were plotted out using R package Plotrix, and gene ontology analysis was done using R package Goseq (Young et al., 2010).