Sentence examples for pa site from inspiring English sources

Deputy Prime Minister Bill English made the announcement at Turangawaewae Marae on Saturday during a special ceremony for the Maori King in which the Crown handed ownership of the Rangiriri pa site back to Waikato-Tanui.

Compound 10 with a benzylamino group at C4 and dimethylated at C1 of the furopyridine ring was the most efficient PA site-specific inhibitor of the c20S (ICcPA50 of 600 nM) without noticeable inhibition of the i20S PA site (iPA).

3′ RACE and Sanger sequencing confirmed that KAT5_icOE mouse cells kept to use only one pA site (corresponding to human proximal pA site) (Figs. 6B and S14).

The bands indicated by red arrows were products from the short (novel pA site) and long (known pA site) isoforms, respectively.

However, our PA-seq data discovered that RNASEH2C has a novel pA site in the 3′UTR (named proximal pA site), resulting in a transcript variant with shorter 3′UTR and not overlaps with KAT5 (Figs. 1A and S2).

Thus in cis overexpression of KAT5 favored the usage of pA site closer to KAT5 promoter (i.e., the distal pA site of RNASEH2C), consistent with the conclusion drawn by Ji et al. (2011).

To explain the higher usage of distal pA site upon elevation of Pol II occupancy, we hypothesize that distal pA site is more sensitive to local Pol II concentration compared to the proximal one.

To investigate further the effect of NAT in controlling pA site usage of the sense gene, we perturbed the expression of NAT gene (KAT5) and then measured the pA site usage in RNASEH2C.

Pearson correlation coefficient (R) between antisense expression level and the percentage of distal pA site usage was calculated.

The experimental results indicated that antisense-mediated regulation of sense gene depended on the overlapped distal pA site.

Moreover, upstream DNA sequence of distal pA site was less conserved than that of proximal one (Fig. S12B).