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During the operation, when the haemoglobin concentration decreases further due to surgical blood loss and concomitant colloid or crystalloid replacement, perfluorocarbon emulsions in conjunction with 100% oxygen ventilation is administered to enhance oxygen delivery and improve tissue oxygenation.
For both heliox and oxygen ventilation, the pneumotachometer was calibrated using a 1-ml syringe according to the manufacturer's instruction.
Unfortunately, prior attempts involving direct oxygen ventilation or aqueous perfusates of fluorocarbons or hemoglobin carriers have failed, leading many researchers to abandon the method.
After induction of anesthesia in a 69-year-old patient undergoing liver transplantation, the patient suddenly developed desaturation, going from 100to90%0% of peripheral oxygen saturation in 50% oxygen ventilation.
Four patients had serious conditions during hospitalization, including pulmonary aggravation requiring oxygen ventilation or transfer to an intensive care unit.
Pure oxygen ventilation induces peripheral vasoconstriction; while this may affect regional perfusion, it could counter-act shock-induced hypotension and reduce vasopressor requirements.
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Tassaux et al. performed a study in 23 decompensated intubated COPD patients that compared two periods of air-oxygen ventilation to one period of helium-oxygen ventilation; all other parameters remained unchanged [20].
As previously reported in similar patients, we observed during air-oxygen ventilation major differences between staticPEEPi and dynamic intrinsic PEEP (dynPEEPi) [23].
Tassaux et al. performed a study in 23 decompensated intubated COPD patients that compared two periods of air-oxygen ventilation to one period of helium-oxygen ventilation; all other parameters remained unchanged [ 20].
As previously reported in similar patients, we observed during air-oxygen ventilation major differences between staticPEEPi and dynamic intrinsic PEEP (dynPEEPi) [ 23].
Multivariate binary logistical regression models were constructed for two previously accepted definitions of severe disease "any need for supplemental oxygen including ventilation" and "any need for mechanical ventilation" [11], [22], [23].
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