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The chaotic conditions and aggressive proliferation of cancer cause oxygen insufficiency [ 56, 57].
Even though fetus has its own natural defense mechanism to tackle the oxygen insufficiency during the delivery, in some cases only timely intervention can prevent adverse consequences.
Evidence demonstrates that dysfunctional mitochondria, not oxygen insufficiency, cause cancer cells to produce inordinate amounts of lactic acid that impact on the treatment of cancer [ 24].
A poor blood supply due to the abnormal outgrowth of chaotically arranged blood vessels frequently results in regions of oxygen insufficiency within tumors.
The moderately increased AST and ALT levels and changes in the BUN and creatinine levels, together with the histopathologic injuries in the liver, kidneys, and ileum, suggest tissue microcirculation dysfunction, tissue oedema, and oxygen insufficiency.
The small, transient increases in brain lactate level evoked by visual stimulation concomitant with increases in total creatine and BOLD signals (Mangia et al., 2007b) probably arise from function-induced changes in relative fluxes of the glycolytic and oxidative pathway, rather than from oxygen insufficiency.
Similar(54)
Therefore lack of blood supply accompanied by oxygen and glucose insufficiency for even a short time period may cause severe damage to the brain.
Both patients had bronchial infection and cough with bronchospasm and moderate respiratory insufficiency (oxygen saturation rate: 90.3% and 88%, respectively) for >1 week.
Influenza with complications: influenza danger signs defined by WHO (including symptoms and signs suggesting oxygen impairment, cardiopulmonary insufficiency or central nervous system complications such as shortness of breath, tachypnea, altered mental status etc).
Exclusion criteria were missing signed informed consent, age <18 years, pregnancy, lung disease with ambulatory oxygen respirator, liver insufficiency (Child-Pugh classification > B), HIV infection, corticosteroid therapy, status post organ transplantation and preoperative signs of infection according to the criteria of the Center of Disease Control, Germany.
The resulting insufficiency of oxygen in the arterial blood supply causes the characteristic symptoms of altitude sickness.
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