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This process contributes to the efficient removal of oxidized proteins and reduces further oxidative damage [73 76].
Oxidative damage to proteins was measured by advanced oxidation protein products (AOPP) as previously described [20].
For many reasons, the brain is highly vulnerable to oxidative damage.
Oxidative damage is characteristic of a wide variety of chronic diseases.
And unlike other organs, it cannot repair itself from oxidative damage.
The brain, he observes, is peculiarly susceptible to oxidative damage.
"So, oxidative damage can produce both too much damaged misshapen protein and, also simultaneously, damage the system that normally clears the damaged proteins from the cell".
"Oxidative damage is a key feature in the aged brains of animals and people," he said, "and the brains of individuals with Alzheimer's disease show greater damage".
Another bit of information linking genetic and environmental causes is that researchers have found that too much alpha-synuclein can lead to oxidative damage.
The "oxidative damage model" argues that this pattern serves to minimize oxidative damage to the tissues.
Fig. 5 Effects of amorphous SiNPs on oxidative damage.
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CEO of Professional Science Editing for Scientists @ prosciediting.com