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A similar study of term labour prediction from the same group demonstrated that two combined biomarkers of oxidative stress, SOD1 and total oxidant capacity, displayed superior predictive efficiency compared to either biomarker alone [ 68].
The aim of this study was to evaluate the oxidative status in patient with Brucella canis (B. canis) and healthy controls by measurement of total antioxidant capacity (TAC) and total oxidant capacity (TOS), and calculation of oxidative stress index (OSI).
In fact, compared to the normal range, oxidant capacity, as measured by means of d-ROMs test, was increased (>300 CARR U) and biological antioxidant potential (as measured by means of BAP test) was decreased (<2200 micromol/L reduced iron).
Electrochemical techniques represent due to selectivity and sensitivity suitable tool for the determination of oxidant capacity in biological blood sample, where these methods are sensitive under the low concentrations of AA affected on the oxidation current peak of Hg II).
NASH is associated with increased oxidant capacity, especially in the presence of liver fibrosis.
Nonalcoholic steatohepatitis is associated with increased oxidant capacity, especially in the presence of liver fibrosis.
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Specifically, shortened telomeres, low telomerase activity, decreased anti-oxidant capacity and increased oxidative stress are correlated with increased psychosocial stress [29] and with increased vulnerability to a variety of disease states [30].
However, defects in anti-oxidant mechanisms and excessive ROS production that overwhelms the endogenous anti-oxidant capacity lead to oxidative stress.
Preservation of morphological structure of small intestine after ligation of mesenteric artery followed by reperfusion was accompanied by decreased oxidative stress and increased anti-oxidant capacity in PACAP-treated animals [97, 98].
Nrf2 is localized mainly in the nucleus of airway epithelial cells and alveolar macrophages in lung and maintains anti-oxidant capacity to environmental or endogenous oxidative stress insults [5].
Neurons are particularly vulnerable to oxidative stress due to their limited anti-oxidant capacity.
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