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Owing to this sequence similarity, PI3Ks may serve as a framework for understanding PIKK function.
Owing to this sequence divergence, only the reads corresponding to the sequence of one of the homologous chromosomes can be mapped, which results in the lower-than-expected coverage.
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This advancement is particularly evident in the model plant Arabidopsis, largely owing to the sequencing and release of its relatively compact genome in the year 2000 [ 5].
Custom panels, however, will likely be smaller than public panels, owing to the sequencing cost required to create them.
This MYBPC3 mutation was not identified by CGC 1 and CGC 8, owing to low sequence coverage in the exon 26 region of this gene, where the mutation was located.
For all remaining WGS strains, there were truncated or absent genes likely owing to sequence errors; however, this would have to be experimentally confirmed.
We know that many datasets are associated with substantial uncertainty owing to limited sequence data collection.
Insignificant matches could be due to dilution of family HMMs, owing to high sequence divergence in entire family alignments.
Importantly, statistical tests indicated that recombination seems to be more substantial within groups than between (Table 1, 2), implying that there is genetic isolation between groups A and B owing to DNA sequence divergence.
These orphan receptors include the NR3B subfamily, named estrogen receptor related (ERR) owing to their sequence homology to the estrogen receptors (ERα/ ESR1 and ERβ/ ESR2) (Giguere, 1999; Giguere, 2002).
Gαo has been classified as a member of the Gi/o family, owing to its sequence homology with Gαi, and is the most abundant Gα protein in brain tissue.
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