These are major discoveries in the field supported by solid experiments; owing to the important implications of these findings, however, it becomes essential to transfer Struhl's approach to a mouse model of tumorigenesis.
Focus on this area, including the implication of this study for the discussion on clopidogrel and proton pump inhibitors is warranted owing to the large clinical implications of a possible interaction between proton pump inhibitors and aspirin.
This result therefore has broad implications owing to the obvious importance of egg survival for lifetime reproductive success, and suggests the need to investigate the development of immune competence more broadly as a function of developmental timing.
Evidence on incremental cost and cost-effectiveness is of particular importance in nAMD, owing to the potential savings and health implications of either reducing treatment frequency or substituting a much cheaper alternative (bevacizumab) for a more expensive drug (ranibizumab).
Preterm birth is a major public health concern, owing to the increased risk for infant mortality, implications for subsequent health, and high economic costs to society [ 24].
However, many health professionals are process illiterate, partially owing to the challenges of recognizing and understanding causal implications of their actions in a system [ 44, 48].
Corrosion control through the use of inhibitors is not recommended for hostile wells because this option has high operating cost implications over the full field life owing to the operating costs of inhibitor injection and the higher frequency of workovers.
It has major implications in the current climate change context owing to the potential to delineate topographic refugia or areas where species could colonize.
Gomes et al. reported that social isolation is associated with elevated tumor NE in ovarian carcinoma patients, a finding that has implications for patient outcomes in ovarian cancer owing to the NE level.
Although results of in vitro assays cannot be directly extrapolated to clinical response owing to the complexity of tumour biology in humans, our findings may have therapeutic implications.
Statistical analysis of the prognostic implications of diploidy was precluded in the present study owing to the low number of patients with diploid tumours (stage I, n=35; stage II and III, n=18).
