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Owing to the evolving concept of NDDs, diagnostic criteria have also changed during the last decades.
Owing to the evolving concept of neurodegenerative diseases, clinical and neuropathological diagnostic criteria have changed during the last decades.
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Mammals represent the most slowly evolving clade but the deuterostome clade shows high variability of evolutionary rates owing to the fast evolving sea urchin and Ciona lineages.
Hence, owing to the recursive channel evolving structure, the required number of tests is (frac {N!}{2^{N-1}}).
This approach has since been used to genetically encode several small dyes,[ 14] but owing to the need to evolve new tRNA/RS pairs and potential size limitations imposed by the translational machinery, larger dyes with enhanced photophysical properties have not yet been encoded.
A nuclear marker that could be considered in future analyses is elongation factor 1α (EF-1α), a conserved nuclear coding gene that can also be used to investigate recent divergences owing to the presence of rapidly evolving introns (Sanchis et al. 2001; Kawakita et al. 2003).
Once a fracture is formed in the serpentinite by hydrofracturing, the activity of Ca2+ in the fluid filling the fracture will decrease owing to the addition of water evolved from the reaction forming the reaction zone.
The fact that most of the mutants that have evolved in these lineages were able to persist in time could be a consequence of the mutational resiliency that evolved owing to the short Hamming distance values.
Specifically, as Denoeud et al. (2010) pointed out, it is likely that many of the putatively missing genes are still present in Oikopleura genome but it is not possible, or easy, to detect them owing to the fact that these genes have evolved so rapidly that they lost obvious resemblance to their vertebrate orthologs.
However, Lukather's role in Toto evolved over time owing to the changing needs of the band.
These processes allow bacteria to adapt to environmental changes or to evolve into pathogens (owing to the distribution of genes encoding toxins, effector proteins, cell wall modification enzymes, fitness factors, and antibiotic and heavy metal resistance determinants).
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