Sentence examples for owing to internalization from inspiring English sources

Importantly, during septic shock, adrenergic hypo-responsiveness often occurs owing to internalization of adrenergic receptors and inflammatory mediator-induced release of potent vasoactive agents (e.g., nitric oxide).

Additionally, high HRG expression may result in a decrease in the apparent levels of membrane surface HER3 detectable through IHC owing to the internalization of the receptor (Hettmann et al., 2010).

Therefore, a possible explanation of our results is decreased protein levels of transporter(s) on the plasma membrane owing to induction of internalization.

This system illustrated how understanding of the VB6 membrane transporter specificity allowed for the design of a VB6-coupled gene transporter with accelerated transfection activity in cancer cells owing to an advanced mode of internalization.

The delivery of both a fluorescence marker (calcein) and antiviral drugs into cells has been achieved owing to a large extent of internalization of cationic liposomes (labelled by Lyssamine-Rhodamine PE or fluorescein-PE) as demonstrated by fluorescent microscopy and quantified by flow cytometry.

In addition, Nos-loaded iron oxide NPs maintained their T2 MRI contrast effect upon internalization into tumor cells owing to their significant susceptibility effect in cells.

DTX/FA-PEG-MWCNTs was found to be significantly more efficient in tumor suppression as compared with plain MWCNTs (non-targeted) as well as drug solution owing to the enhanced drug release from endosomes after internalization.

Such GSLs with shorter headgroups may more often serve as receptors, owing to the close proximity with the bilayer membrane, facilitating internalization.

Compared with the disadvantages of naked shRNA such as fast degradation, short half-life, and difficulty in penetrating the cell membrane owing to the negative charge, gene-loaded protamine nanoparticles with the positive charges facilitated the internalization of cells through endocytosis and macropinocytosis and enhanced the transfection of shRNA in vitro in A549 cells [21,22].

Nevertheless, owing to the affinity of SPC to cells, the polymer-lipid hybrid NPs might further enhance the internalization of drug.

Turnout was low, owing to the snow.