Sentence examples for owing to a specific from inspiring English sources

It is thought that the cyano substitution of CMPD3 may increase the potency against EphB3, owing to a specific interaction of the cyano moiety with Cys, or a reduction in steric clash compared with the morphiline of CMPD2.

Here, we found that in M2 macrophages P2X7R activation induces only a weak ROS response that may be owing to a specific uncoupling from recruitment of the NADPH oxidase complex without alterations in P2X7R up-stream signalling, correlating with the low level of NLRP3 activation and IL-1β release found in intermediate polarized macrophages after ATP/P2X7R stimulation.

Owing to a specific Michael addition between thiols and the double bond of nitroolefin moiety, probe 1 displayed a high selectivity toward GSH.

Both schemes individually are mass conservative and can be used within single-step or multi-step coupling algorithms that ensure overall mass conservation owing to a specific design of the interface fluxes in the multi-step case.

Echinocandin B, which is produced by Aspergillus nidulans and Aspergillus rugulosus [30], has an antifungal activity owing to an specific inhibition of the synthesis of 1,3-β-D-glucan, a major component of the yeast cell wall [31].

In conclusion, these findings suggest that powdery mildews possibly lack the ability to form hyphal anastomoses owing to a lineage-specific loss of at least two genes coding for proteins that are essential for this process.

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of cells that have been shown to inhibit T-cell responses in tumor-bearing mice, but little is known about these cells in humans owing to a lack of specific markers.

The neurosphere assay represents a method to detect the presence of neural stem cells, however owing to a deficiency of specific and definitive markers to identify them, their quantification and the rate they expand is still indefinite.

34 43 44 Furthermore, owing to a lack of a specific 'gold standard' tool to measure informed consent comprehension, we could not examine concurrent (criterion) validity in which participants' scores on DICCQ could be compared with the participants' scores on the 'gold standard' obtained at approximately the same point in time (concurrently).

All these results indicate that non-homogeneous models can capture a genuine timewise variation in composition and that the pattern of parallel increase to high temperatures does not result from a bias owing to a correlation between site-specific rates and site-specific compositions [ 17] but emerges in spite of this bias.

In vivo assessments of immune function (i.e. innate and adaptive responses) following influenza virus infection have been primarily limited to the mouse model owing to a lack of ferret-specific reagents and incomplete genome sequencing of this species.