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We were unable to find a comprehensive list of possible adventitious agents when ovine materials are used, as is the case for the Lister strain smallpox vaccine produced in Europe and old vaccine stocks held by some European countries for biologic defense.
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In this work we performed interlaboratory validation of a Taqman real-time PCR method for the identification of bovine and ovine material.
Subsequently, the technique was used to quantify the antibody titre in ovine serum, which is used as feed material by BTG PLC for manufacturing FDA-approved polyclonal bio-therapeutics.
Some viral vectors at the earliest stages of testing as delivery vehicles for HCV genetic material include alphaviruses, canary pox, ovine atadenovirus and semliki-like viral particles [81-84] [81-84]
This determined that ovine tendons were too small to insert the suture materials in the in vivo configuration and as a result bovine tendons were used.
Single leaflet replacement utilizing an ovine model is an attractive approach in that candidate materials can be evaluated under valve level stresses in blood contact without the confounding effects of a particular valve design.
The sheep (ovine) model is one commonly used for in vivo trials of materials for cartilage repair (Kon et al. 2010a; Milano et al. 2010; Guo et al. 2004).
Epidemiological data regarding the distribution of ovine chlamydiosis in Germany are scarce and are based solely on materials submitted for routine laboratory examination [ 9- 12].
This study shows that digestion of plant material and release of transgenic DNA can occur in the ovine small intestine.
The BSE lesion profile in RIII mice is independent of the source of the BSE agent (direct transmission from bovine- or ovine- or porcine-passaged BSE), inoculation of CNS or non-CNS material, inocula prepared from experimental or natural cases, inocula derived from pooled material or individual brains (20), or the titer of the inoculum (19).
This means that the ovine acetabulum anatomy is an ideal model to test the efficacy of bioactive material against sclerotic bone at the rim.
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