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During infection with 2×106 pfu LCMV-WE, overwhelming replication of LCMV leads to partial deletion of the NP396 epitope-specific CD8 T cell repertoire (Figure S3).
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Still, overwhelming is overwhelming.
The lon gene deletion is essential to impair Salmonella replication and avoid overwhelming systemic disease in the host.
Furthermore, vitamin C reduces the overwhelming neutrophil response and inhibits bacterial replication.
Current data storage and replication systems fail at both coping with such overwhelming amount of heterogeneous data and at satisfying the stringent requirements posed by this technology (i.e., dynamic nature of the physical resources, continuous flow of information and autonomous behavior demands).
Successful transmission to non-human primates and transgenic mice expressing the human prion protein (human PrP) with replication of major features of the vCJD phenotype, provided overwhelming evidence supporting the notion of cattle-to-human transmission [8] [10].
This is most probably a reflection of the abrupt and massive virus replication in the lungs following intratracheal inoculation, which in turn induces an overwhelming and simultaneous production of several cytokines.
"It was completely overwhelming, despite having prepared for weeks for it," says Brian Nosek, a psychologist at the University of Virginia in Charlottesville who led a massive replication of psychological science published in Science in August—No.
Compared with the chromosome, the overwhelming majority (greater than 80%) of the orc/ cdc6 genes in the extrachromosomal elements (minichromosomes and megaplasmids) are associated with predicted replication origins (Table 1).
The replication is meticulous.
Sound overwhelming?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com