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The primary response observed was the overwhelming induction of TLR2 to counteract B. pseudomallei, which we propose, subsequently triggered the activation of many inflammation-biased genes important in attracting neutrophils and monocytes to the site of acute inflammation.
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In this layout, the expression changes of all genes were color-coded, showing the overwhelming induction (upregulation) especially at 18 h after M. tb infection).
When ROS accumulate, oxidative damage is normally prevented by induction of protective factors like antioxidants, which may not be effective if the insult is too overwhelming.
While the overwhelming evidences pointed to the alteration of actin cytoskeletal organisation as the common target, several reports showed that the induction of apoptosis is mediated through JAK2/STAT3 signaling pathway.
It's an induction of fire.
These findings suggest that TL1A gene variation exacerbates induction of TL1A in response to FcγR stimulation in Jewish CD patients and this may lead to chronic intestinal inflammation via overwhelming T cell responses.
VP16-dependent induction of the ICP0 gene.
By contrast, deletion of Cox1 did not alter the cytokine response to LPS, perhaps reflecting an overwhelming Cox2 induction by this stimulus (Fig. 1).
In this context, the overwhelming majority of studies have used induction paradigms which consist of constant frequency stimulation patterns, like paired pulses, a tetanic stimulus or a theta burst protocol.
The overwhelming majority of them were civilians.
The overwhelming majority of Omanis are Muslims.
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