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"This is overwhelming damage control," Lieberthal said.
Given the overwhelming damage to the building, the students were divided among four schools in three nearby districts.
What comes next will be the assessment of the overwhelming damage to the Gulf Coast economy and environment and the long process of repairing that damage.
An insult to the cellular blue print by several anticancer drugs initiates an orchestrated response coordinated by sensor, transducer and effector proteins that detect the damage and activate either a repair mechanism or an apoptotic program in case of overwhelming damage.
The fact that the Cdk1/Cdc5/Mus81 pathway is driven by mitotic kinases and is not affected by the damage checkpoint-mediated DDR, together with its crossover-prone nature, suggests that this late resolution pathway acts as a last resort option to allow proliferation, resembling the phenomenon of damage checkpoint adaptation in the face of persistent or overwhelming damage (Pellicioli et al, 2001).
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By contrast, high ROS content above that required for signaling may cause overwhelming oxidative damage that can culminate in senescence or death in both normal and cancer cells.
But, Boies says, "There is overwhelming evidence of damage to gay and lesbian couples who cannot marry and to their children and no evidence that permitting gays to marry damages heterosexual couples.
But, Boies says, "There is overwhelming evidence of damage to gay and lesbian couples who cannot marry — and to their children — and no evidence that permitting gays to marry damages heterosexual couples.
Importantly, in both HBV and HCV infection, regulatory CD4+ T cells have been suggested to contribute to the protection from overwhelming liver tissue damage, but also to the failure of CD8+ T cells.
But might this sudden, overwhelming success be damaging to a first-time novelist?
But with some disasters, like this week's tornado in Moore, Oklahoma, the concreteness of the damage is overwhelming.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com