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Consider "Daria: Is It Fall Yet?," in which she finds herself forced into volunteering at the O.K. to Cry Corral, a summer camp for the overtly sensitive -- and those who aspire to be.
Interestingly, bidirectional motion of RNPs is not overtly sensitive to inhibition of dynein's ability to hydrolyse ATP.
In contrast to upf2∆ and rpa34∆, deletions of ptc1 and two uncharacterized genes, SPAC607.02c and new13, were not overtly sensitive to HU but were very sensitive to bleomycin.
Moreover, the GGGGCC expression constructs without ATG start codon and GGGGCC repeat based poly-GP construct were not toxic, suggesting HEK293 cells are not overtly sensitive to either C9orf72 repeat RNA or protein toxicity under our conditions.
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The artwork was not overtly political, but given the sensitive context to development in China, it did have a certain edginess.
Time, however, is working against them, including the overtly macho Diaz Frank Grilloo); the strong-yet-sensitive Talget (Dermot Mulroney); and the easy natured but tough-as-nails Henrick (Dallas Roberts).
It mentioned concerns over her "overtly sexualized image" that is not "culturally encompassing or sensitive".
That question brings to mind a possibly apocryphal story from a number of years back about a survey in which women were asked to choose between a suave, politically correct Alan Alda, who was famously sensitive to feminist issues, or the rougher-looking, more overtly sexy Kris Kristofferson.
This gene is involved in DNA damage induced germ cell apoptosis upon UV and ionizing irradiation (IR) and is required for mitotic germ cell cycle arrest upon UV treatment but does not overtly affect DNA repair as cep-1 mutant worms are only very weakly sensitive to UV and IR in organismal radiation survival assays [ 5- 7].
Notably, successful testis determination in Map3k1ΔKD homozygotes is not overtly disrupted by the further removal of a single copy of Map3k4, a known dosage-sensitive sex-determining gene in the mouse that also functions in the MAPK signalling pathway to activate JNK and p38 [45] [45], [45].
This effect on experience-dependent neural plasticity occurred at much lower exposure levels than did the overtly toxic effects of MAM seen under standard conditions, suggesting that impairments in neuronal plasticity may be a more sensitive index of neurotoxicant exposure than are the toxicant's direct effects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com