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However, this obstacle may be complicit with other more overt limitations.
"I wish we had a longitudinal study to draw on," said Haas. "For a while, [researchers] thought that the cultural climate improved and LGBT people weren't facing the same overt limitations and discrimination.
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Due to their limited reserve and limitations in dynamic variability even with minimal overt respiratory signs, this capacity may change during phases of distress.
Another limitation regards the low reliabilities of the eight subscales measuring the overt and covert cognitive distortions, which was probably due to the limited amount of items covering each subscale.
Despite this potential limitation on the precision of our frequency estimates, there was no overt enrichment of particular variants beyond expectation.
These limitations explain the wide range of outcomes after BCR with some men progressing to overt metastatic disease and death despite therapy and others dying of other causes even without further prostate cancer intervention [ 83].
The third limitation is the presence of multiple reference standards including CXR for pseudolesions or overt benign lesions, and CT or histology for positive pulmonary lesions.
Due in part to limitations in standard toxicity testing methods at the time, the critical effect was typically an overt toxic effect, resulting in an endpoint now referred to as an "apical effect", and often had direct clinical relevance.
One limitation of the current study was the smaller number of subjects with macroalbuminuria or overt nephropathy and those requiring hemodialysis.
A limitation is that we were not able to divide hypo- and hyperthyroidism into its overt and subclinical forms due to the lack of free triiodothyronine and free thyroxine levels.
Although placebo-controlled clinical studies demonstrate that the H2RAs significantly reduce the risk of overt and clinically significant GI bleeding in critically ill patients [ 5, 8], these agents have a number of limitations concerning efficacy.
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CEO of Professional Science Editing for Scientists @ prosciediting.com