Sentence examples for overt increase from inspiring English sources

Phosphorylation of calpain 2 following epidermal growth factor receptor signalling occurs through the MAP kinase pathway involving ERK and MEKK1 and requires no overt increase in cellular Ca2+ [12], [12].

We did not observe an overt increase in active caspase-3 until 24 hours in these lysates (n = 4 at 0, 4, 12, 24 hours), suggesting that activation of apoptosis does not occur until after peak levels of permeability.

Interestingly, the BRAF V600E mutation in grade II PXA did not result in an overt increase in levels of phospho-ERK for mutated tumors (mean score 2.4 for BRAF V600E-positive Grade II PXA and 3.1 for BRAF V600E-negative Grade II PXA; p value 0.13).

There is also an overt increase in expression in projections to or from the periesophageal neuropil.

Interestingly, although there was clearly an increase in SJ-associated membrane markers there was no overt increase in levels of any of the three SJ proteins examined.

Because these patients exhibit an overt increase in microvascular permeability, sustained high cytokine levels are apparently not mandatory for the development of oedema.

The prevalence of overt hypothyroidism increased with the increase in BMI (P for trend <0.001).

Overt controls increase in line with the amount of credit.

Several arguments were made for identifying as a distinct group women with overt diabetes: Increased risk of congenital anomalies in offspring (51 ).

We postulate that hyperinsulinaemia which prevails during initial phases of insulin resistance (condition prior to overt diabetes) increases bioactivity of free IGF-1, which may contribute to process of carcinogenesis.

In the Pittsburgh EDC Study, overt DN increased the risk of ischemic stroke 4.4-fold, but not the risk for hemorrhagic stroke, possibly due to the low number of cases (15).