Sentence examples for overt adverse effects from inspiring English sources

In the rats, neither the single dose nor the five daily doses of AFM tartrate produced overt adverse effects clinically.

The toxicity studies in rats showed that a single iv dosing of AFM tartrate at 987 μg/kg (1,000× human dosage) or repeated iv dosing at 98.7 μg/kg/day (100× human dosage) for 5 consecutive days did not produce overt adverse effects clinically.

The results showed that a single iv dosing of AFM tartrate at 987 μg/kg (1,000× human dosage) or repeated iv dosing at 98.7 μg/kg/day (100× human dosage) for 5 consecutive days did not produce overt adverse effects clinically.

The results showed that intravenous administration of AFM tartrate to rats for a single day at 98.7 or 987 μg/kg (592 or 5,920 μg/m2, 100× or 1,000× the proposed human dose of 8 μg, respectively) or 5 consecutive days at 98.7 μg/kg/day (592 μg/m2/day, 100× human dose, total dose of 493.5 μg/kg) did not produce overt adverse effects clinically nor had any detectable toxicity on any target organ.

In fact, stereotaxic injection of high concentrations of cannabinoids will eradicate a significant portion of C6 astrocytomas inoculated into rodent brains without affecting healthy surrounding tissue or inducing overt adverse effects [8].

Given that we observed no overt adverse effects of PRN exposure on APC function, we directed our attention to whether PRN exposure interferes directly with CTL function itself.

From this, one might conclude that the correlations are not predictive of an overt adverse effect.

With more than 10,000 treated patients no overt adverse side effects have been reported for Gendicine®.

However, it is important to acknowledge that tenofovir gel has been evaluated in multiple studies that have not observed overt clinical adverse effects.

In contrast, our results suggest that subclinical LV dysfunction and subsequent overt heart failure is partly due to adverse effects of IR in patients with AVS.

The most reasonable explanation is that the apparent adverse effects associated with low BC levels are secondary to overt or occult comorbidity and frailty.