Sentence examples for overload stress from inspiring English sources

Irritable bowel syndrome has a variety of symptoms (constipation, diarrhoea, cramps, indigestion, bloating, nausea) and causes (food allergy, infection, toxic overload, stress), but it is possible to become symptom-free.

The loading conditions (baseline loading ratio R, baseline stress intensity factor range ΔK and overload stress intensity factor Kol, Rol) are also required.

In response to pressure overload stress (an experimental model of hypertension), DN-Lats2 Tg mice were protected against cardiomyocyte apoptosis and showed an enhanced hypertrophic response, i.e., individual cardiomyocyte enlargement leading to greater overall heart mass [135].

All of the TAC-induced pressure overload stress lasted for 3 weeks.

Indeed, transgenic mice overexpressing Trx1 specifically in the heart had reduced cardiac hypertrophy after overload stress compared to wild-type mice [22].

Following the concept of Zhang and colleagues [8], increased expression of NOX4 is protective against chronic overload stress with the specific function to preserve myocardial capillary blood flow by inducing angiogenesis.

However, we explain that the most likely extensive axial load-type stress on the talus, which occurs in full-weight bearing plantar flexion (for example in en-pointes and demi-pointes positions), can potentially cause overload stresses on the anatomical structures (trabecular system, vascular system) of the bone.

To determine the consequence of persistent miR-499 expression in pressure-overload stress, we first generated transgenic mice with increased levels of miR-499 in the heart by expressing miR-499 under control of the cardiac, alpha-myosin heavy chain (Myh6) promoter, as it confers increasing postnatal ventricular cardiomyocyte expression [42] [44].

The above two studies show controversial data because of different chemistries and dose and at different times after the initiation of pressure-overload stress it is conceivable that miR-25 could play a beneficial role acutely by helping the heart adapt to pressure stress but produce long-term maladaptive effects.

In conclusion, we found that tomoregulin-1 plays a protective role in the maladaptive hypertrophy caused by pressure-overload stress, and TGFβ non-canonical (TAK1-JNK) signaling is one of the pathways involved in the regulatory effect of tomoregulin-1 on cardiac hypertrophy.

Application of the developed methodology confirms that extreme weather, extreme workplace temperature, high ship motion, high level of noise and vibration, and work overload and stress increase the likelihood of human error as well as potential accidents.