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The clusters annotated in this way were overlayed with HDAC consensus genes or TF genes known to be up-regulated on DoD6 versus DoD0.
Consensus 3D-pharmacophore overlays are useful for rationalizing 3D-structure-activity relationships and can also be used to perform hit identification, scaffold hopping or lead optimization by virtual screening of diverse or focused compound collections using pharmacophores.
The overlay of the lead compounds from the initial round (BAF4, BAF8, and BAF11) elucidated the consensus of polar and nonpolar interactions at fiber binding interfaces, which sheds light on the amyloid pharmacophore.
We emphasized the degree of consensus among species distribution models regarding prediction of suitable climate for the species by overlaying the mapped predictions of each model to create a spatial frequency distribution.
The motif was identified by overlaying the binding sites of Zfp57, Kap1 and Setdb1, identified by separate ChIP-seq experiments, and computing the consensus sequence over all sites occupied by all three proteins.
My overlay is there".
Politics overlay the courtroom battles.
An overlay of commentary would improve discovery.
Just overlay the photo with vertical bars".
In one transparency overlay in "Life?
TRACKLEMENTS TOMATO AND PEPPER Peppery, vinegary overlay.
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