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Analysis using ANCESTRYMAP yielded a maximum LGS score of 4.428 at SNP rs7286127, whose physical location is 34.8 Mbs, and overlapping the set of significant SNPs obtained using ADMIXMAP.
The set of neurons discriminating between one texture pair was found to be independent of, and partially overlapping, the set of neurons encoding the discrimination between a different texture pair.
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Of the 42 published STE20 genetic interactors, five of the corresponding GINs significantly overlap the set of predicted substrates (adjusted P ≤0.05, hypergeometric test; Table S5).
We hypothesized that the set of genes responsive to benzoate would overlap the set of genes responsive to external pH in the mild acid range (pH 6 versus pH 7) as reported [31].
Interestingly, only miR-572 and miR-190 from the set of 15 miRNAs most closely associated with EFS and OS overlapped the set of 37 miRNAs that were associated with MYCN amplification.
Although only one of the Ste20p PINs (i.e. the neighborhood of Cdc28p (significantly364)) significantly overlaps the set of predicted substrates (adjusted P ≤0.05, Fisher's exact test; Table S6), the 29 PINs tend to have lower overlap P values than the PINs of the other proteins in the network (Figure 3C; P ≈8.29×10−4, Mann-Whitney test, see Materials and Methods).
To address this issue, we overlapped the set of K562-unique promoter distal Kaiso peaks with the top 20% of the Pol2 peaks from K562 cells.
This is possible because the nature of the transcriptional regulatory network as determined by genome-wide location analysis data reveals that some transcript factors highly overlap the set of genes on the microarray [ 14].
The remaining annotations were annotated by finding reads that overlapped the set of repetitive elements in both diatoms, provided by Florian Maumus (INRA, Versailles, France), and also the set of predicted genes available for each genome.
Notice that the dashed line does not overlap with the set of credence functions that accuracy dominate yours at any point.
Consequently, the interaction neighborhood of a frequently studied gene/protein is more likely to significantly overlap with the set of predicted substrates.
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