Exact(2)
We examined overlapping of ChIP-seq-derived STAT1 binding regions, identified by Gerstein's group [11], with 83 predicted microRNA promoters.
To see the effect of transcription factor on bidirectional region, overlapping of ChIP-seq-derived STAT1 binding regions, identified by Gerstein's group [ 11], with the regulatory regions of four types of promoters (Additional file 3, 4, 5 and 6) were explored.
Similar(58)
Among these, promoter regions of 41 microRNAs (49.4%, Supplement Table S1) contain or overlap with ChIP-seq-derived STAT1 enriched regions; this finding is statistically significant when we repeated permutation analysis 10,000 times, and calculated the possibility that 41 out of 83 randomly-selected regions overlap with STAT1 binding regions (P-value <10−39).
In the aforementioned example, GAT will compute the overlap of ChIP-Seq binding events and DNaseI-hypersensitive sites.
Let m denote the number of the BEs counted by a peak-finding program (e.g. T2G) in a DNA fragment cluster overlap of ChIP-seq library.
Given that lamin A/C also occupies euchromatin regions18, we analyzed the degree of overlap between both sets of ChIP-seq data.
These data suggest that the counts of overlapping ChIP-seq tags are quantitatively reproducible by independent experiments.
The heatmaps between the summary plots depict how much of each enhancer region overlaps with ChIP-seq peaks of MSL2 or KANSL3.
We selected 20 positive peak intervals identified by HLH-1 ChIP-chip, 17 of which overlapped with ChIP-seq called peaks.
This is supported by far higher overlap of ESR1 ChIP-seq peaks in primary cancer cells with cell line ChIP peaks found in multiple datasets.
Overlap of AR ChIP-seq replicates was comparable to previously described cell line data (Bolton et al, 2007; Jia et al, 2008).
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