Also, recognition of the overlapping features in AAS will allow a more comprehensive understanding.
Given the vital role of imprinted genes in development, the fact that many known imprinted genes are expressed in the brain, and evidence of overlapping features in autism and imprinting disorders, we investigated the effect of incorporating allelic parent-of-origin into an autosomal linkage scan for autism.
In addition to the well-defined differences in cell origin and size, extracellular vesicles can also exhibit differences or show overlapping features in their molecular compositions and functions.
Altogether, these observations suggest that the overlapping features in Rett syndrome may be caused by impairment of common or intersecting biological pathways downstream of expression in the brain.
Although some of these ncRNA species show overlapping features in plants and animals, the information concerning their evolution and functionality is still limited [ 8].
Therefore, in order to make it easier to deal with overlapping features in the Gene Builder, a checkbox for each transcript can be used to show and hide them in the main Artemis window.
More than 50 signalling cascades (see Additional file 2), mainly due to overlapping features in the existing maps, were initially identified to be of interest in further downstream analysis based on their potential functional relevance.
Researchers have shown an increased interest in the overlapping features between these disorders, including attention deficit [Mayes et al., 2011; Sturm, Fernell, & Gillberg, 2004], behavior problems [Mayes et al., 2011], and difficulty in social skills [de Boo & Prins, 2007].
The differential diagnosis of GATA-2 deficiency includes other related disorders with overlapping features and are summarized in Table 1.
With the number of high-throughput experiments characterizing genomic features across the entire genome increasing, e.g. histone binding sites and transcription factor binding sites, one of the most common exploratory analyses is examining for overlapping features, or lack-thereof, in specific regions of interest.
