Although various overlapping risk factors exist between cerebrovascular incidents and cardiac incidents, stroke therapy has largely neglected the cardiac pathological consequences.
Another explanation is that the association between early cannabis use and educational attainment is not causal, but the result of overlapping risk factors that increase the likelihood of both early cannabis use and disengagement from education.
Another model of overlapping risk factors is the dimensional account of ASD by Ronald et al. (2006).
Overlapping risk factors for both AD and vascular disease support a role for systemic microvascular dysfunction in the pathologic changes that occur during AD pathogenesis.
These findings may provide clues into the etiology of all three conditions and may point to overlapping risk factors or treatments.
In both cohorts, overlapping risk profiles of ideators and attempters may indicate that ideators should be carefully evaluated and monitored, particularly those with depressed moods, alcohol/substance abuse disorders, and inadequate treatment continuity.
The same set of multiple genetic variants of small effect were also associated in a bipolar disorder sample, supporting findings for overlapping risk between these disorders from family-based epidemiological studies [ 7].
There are other models of overlapping risk factors that have been proposed in the literature, but in all cases they predict that relatives of those with comorbid ASD+LI should have an increased rate of language impairments.
This suggests that overlapping risk factors (eg, being Māori, having long-term DM2 and having family history of CVD, in which case 5% adjustment is applied only once) may dampen the CVD risk score, possibly underestimating extremes of risk observed in some individuals.
Our study design enabled us to assess the co-occurrence of cardiometabolic risk factors in a large hypertensive study population representing a "real-world" setting among physician practices across the US, and to estimate the impact of specific overlapping risk factors on BP control.
