Exact(1)
After inspection of the Schoenfeld residuals we conclude that the overlap of age categories is very minor, and we proceed without altering the models.
Similar(59)
The overlap of age-associated differential gene expression in HPC and MSC was moderate.
As would be predicted by our findings of a "prematurely aged" gene expression profile in AD, we found a statistically significant overlap of age-correlated genes and AD-associated genes (p = 3.34×10−4 by Fisher's exact test).
Similarly, in FTLD-TDP, where we also found a "prematurely aged" gene expression profile, we observed a statistically significant overlap of age-correlated genes and FTLD-TDP-associated genes in both FTLD-TDP patients with GRN mutations (p = 2.02×10−6 by Fisher's exact test) and FTLD-TDP patients without GRN mutations (p = 1.21×10−4 by Fisher's exact test).
However, most study pairs with normal samples showed significantly greater degrees of overlap of age-associated CpG loci than would be expected by chance.
In the case of cancer samples, the degrees of overlap of age-associated CpG loci between study pairs were also significant, but less so than for normal samples.
In analogy, each dataset was analysed separately and the overlap of age-associated changes supported the notion that they occur in different tissues.
This results in an increasing overlap of ages in the mother cell populations harvested at later time points, as modeled for a starting cohort of 1000 cells (see methods: Harvesting time points ).
Patients' characteristics between the derivation and validation cohort were similar, although patients in the derivation study were younger (median age, 83.1 year vs 87.5 year, (p = 0.011) on average with a large overlap of the age range.
Owing to the overlap of the age distribution of seminoma and non-seminoma cases, the majority of controls matched to both seminoma and non-seminoma cases.
An overlap of the age-regulated genes between tissues was assessed using unique Entrez IDs (Additional file 1: Table S3).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com