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The overlap in strain sampling is minimal.
The lack of overlap in strain genotype could indicate the existence of infant-specific strain sources (e.g. mothers), and barriers that prevent spread of those populations to other infants in the NICU.
Although the prevalence of C. difficile in raccoons did not differ between location type (farm or conservation area), there was little overlap in strain types between farms and conservation areas.
Similar(57)
Note the persistence of specific genotypes within infants and the almost complete lack of overlap in strains between infants.
Apart from the small overlap in strains found between our study and that of Routolo et al., many of the same pathways were found overrepresented in both studies.
While housing and cost has limited widespread use of the model, the recently discovered overlap in strains recovered from man and pigs suggests that these animals may provide the ultimate model for this disease.
There was >90% overlap in genes, strains and QTL between the two portals.
There is, however, likely some degree of overlap in both strains' response to pathogen exposure due to the fact that several genes were up-regulated in both Hofer and Trout Lodge (i.e., ubiquitin-like protein 1, IRF-1, and PPAR-α-interacting protein Gig2).
The changes in gene expression in the tra1- SRR3413 strain partially overlap those seen in strains with deletions of SAGA or NuA4 components and result in phenotypes consistent with the involvement of Tra1 in cell wall stability and stress response.
The response duration distributions do illustrate an overlap in response properties across strains, for example, the briefest T → A responses are similar to Rho responses both in kinetics and duration.
Assuming strains are relatively similar (sequence divergence based on mitochondrial cytochrome oxidase I is ~2% [ 24]), the degree of overlap in transcriptome sequence datasets between strains was relatively small (~15%), potentially indicating a high degree of under-sequencing in both cases.
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