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Another promising approach to overcome radiation resistance is using small interfering RNA (siRNA) to target related pathways.
An understanding of this phenomenon can lead to the design of new glasses which overcome radiation with a minimum of density change.
In addition, Sal can overcome radiation resistance via inhibition of the Wnt/beta-catenin signaling pathway [ 23].
We next determined whether a Rac1 inhibitor could help to overcome radiation and/or cisplatin resistance in HNSCC cells.
If therapeutic compounds were capable of resensitizing resistant tumours then a concurrent chemo-radiation treatment could be used to overcome radiation resistance.
This lack of clinical efficacy of PC irradiation, combined with the substantial benefit that efficacious PC EBRT could provide, mandates exploration of methods to overcome radiation resistance in PC.
Overall, curcumin provided Drosophila with augmented resistance to overcome radiation-induced oxidative stresses.
About 2000 transformed cells were subjected to the ionizing radiation treatments, and 32 colonies overcoming the radiation-induced stress were analyzed by psbA sequencing.
The list of the game's greats who have played through excruciating pain is long: Crosby's mentor and boss, Mario Lemieux, overcame radiation treatments for Hodgkin's lymphoma and a deteriorating spinal condition that left him unable to tie his own skates.
In order to overcome hypoxic radiation resistance and improve prognosis after radiotherapy, feasible and efficient methods to predict clinically significant tumor hypoxia need to be identified [ 3– 5].
The goal of biologically adapted RT or dose painting is to individually adapt the radiation dose to biological features of the tumor as non-invasively assessed with functional imaging in order to overcome increased radiation resistance.
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