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This review describes the current status of clinical trials related to siRNA-based cancer therapy, as well as the remaining issues that need to be overcome to establish a successful therapy.
The unified framework for invasion biology proposed by Blackburn et al. (2011) recognises that the invasion process can be considered as discrete stages and that there are barriers a species must overcome to establish and subsequently spread.
If we can find a combination of treatments (e.g. antibiotic, antibiofilm, or antimicrobial) that can target all of the primary or predominant populations in a wound then we have introduced a potentially larger barrier that the very minor populations must overcome to establish their own niche.
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Major hurdles have been overcome to successfully establish Timor-Leste's first health research institution.
PERSEVERANT MOGUL Trump is a "successful businessman and billionaire," who's "worked hard," "taken risks," and "overcome failures" to establish "a huge personal empire".
By 1917 he had overcome British suspicions to establish a spy ring, including his sister, Sarah, that passed on information about the Turks in Palestine.
Mr. Alawi and the other appointees -- who are expected to be named shortly -- will have to overcome serious obstacles to establish legitimacy in the eyes of Iraq's people.
She had studied hard and aced college and law school; she had overcome many hurdles to establish herself — who in America would care that her grandfather was one of the founders of the Chinese Soviet Republic?
High corrosion rate is one of the major obstacles that have to be overcome in order to establish practical application of primary alkaline Si air batteries.
In this review, we will focus on the mechanisms used by the innate system of the host to detect and eliminate mycobacteria and the strategies used by M. tuberculosis to overcome host responses to establish a successful infection.
It is here proposed as an information barrier which needs to be overcome in order to establish communication between sequences and structures.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com