Although the appointment of a Chief Nursing Officer at the beginning of 2014 is encouraging, a lot of effort is needed to overcome the implementation inertia characteristic of policy-making in South Africa (53).
In the second half of the 1990s, a major hurdle in gene therapy was overcome through the implementation of new viral vectors, which prompted the neuroscience community, and me as a Ph.D. student, to begin using viral vectors to deliver genes to the brain.
However, there are major hurdles to overcome before the implementation of these tests in clinical laboratories with reference to type of test, technology and equipment to be employed, and issues such as cost effectiveness, accuracy, reproducibility, personnel training, reimbursement by third-party payers, and intellectual property.
Once these are overcome however, the implementation of the new WHO smear microscopy policy recommendations together with LED-FM could substantially reduce the workload and increase case detection.
This shortcoming could be overcome by the implementation of a borderline zone for the interpretation of QFT-GIT results.
Studies identify physicians as a barrier to be overcome in the implementation of, especially administrative, IT innovations [ 13].
However, these challenges may be overcome by the implementation of biodegradable nanoparticles such as those championed by Green and colleagues.
41 However, the short time period between diagnosis and treatment, and the lack of training in this field by dental professionals, are among the barriers to be overcome in the implementation of this proactive approach.
However, there are practical problems to overcome for the implementation of double haploids in aquaculture breeding schemes, including biases from non-additive gene effects costs and other practical constraints.
By varying degrees, all of these factors are, therefore, likely to introduce bias [ 16] and whilst some of these difficulties can be overcome with the implementation of more sophisticated survey designs [ 17], in many cases these are expensive and difficult to implement [ 18].
Singly or in combination, environmental designs in the retail industry, such as increased lighting to improve visibility and a limited cash-handling policy, can make workers safer, but more research is needed to overcome the barriers to implementation of environmental designs, especially in small businesses.
