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What is going on is that the program has not been able to overcome substantial obstacles standing between it and success.
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Mexía overcame substantial obstacles, including emotional instability, to pursue her love of plants.
Senator Kennedy will have to overcome substantial legislative and constitutional obstacles to see his bill become law, and even then he may be foiled by an even more implacable foe in this election year -- time.
Although this pilot project demonstrated success, national adoption and scale up requires overcoming some substantial obstacles.
Ms. Bachmann would have substantial obstacles to overcome.
"I hope there will be no premature, self-congratulatory statements suggesting the crisis is over, for we all know that there are still substantial obstacles to overcome.
"There are still substantial obstacles to overcome: the growth figures remain low and the tentative signs of growth are still fragile," he said.
"For we all know that there are still substantial obstacles to overcome: the growth figures remain low and the tentative signs of growth are still fragile".
However, it is important to keep in mind that the need for a decision support infrastructure represents just one of several substantial obstacles that must be overcome before genomic and personalized medicine can become routine components of clinical care.
Hulu must still overcome some significant obstacles.
Still, he faces substantial obstacles.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com