Sentence examples for overcome resistant from inspiring English sources

Certain populations of the soybean aphid have adapted to overcome resistant genes in newly developed soybean lines [43], [44], [45], [46].

These results suggested that K-11 scFv might overcome resistant problem caused by D49A amino acid replacement.

These data for this particular regimen do not support basic tenets of metronomic chemotherapy, such as the ability to overcome resistant tumours by targeting the endothelium.

In these cases it may be necessary to release several successive gene drives, each targeting multiple sites, to overcome resistant alleles as they emerge.

The data with this particular combination do not support the basic tenets of metronomic chemotherapy, such as the ability to overcome resistant tumours by targeting the vessels.

Part of P. infestans success is accounted for by its biological lifestyle and remarkable capacity to rapidly adapt to overcome resistant plants [ 3].

To identify methods for overcoming resistance, resistant and parental sensitive cells were compared pre-treatment and post-treatment to identify mechanisms leading to the resistant phenotype as well as investigate their differential response to SINE compound treatment.

As reduced cellular uptake is a well-known resistance mechanism of cisplatin we explored the potential to overcome resistance in cisplatin-resistant A2780 ovarian carcinoma cells by means of macromolecular prodrugs exploiting endocytosis as alternative uptake mechanism.

This indicates that iron II) glycine sulfate is not a typical resistance modulator comparable to modulators of multidrug resistance, where modulating agents completely or partially overcome resistance of a drug-resistant sub-line to a cytostatic drug towards the level of a parental drug-sensitive cell line [25].

Our findings indicate that therapeutically targeting HUNK is a potential strategy for overcoming resistance and that resistant breast cancer cells maintain HUNK expression to drive tumorigenesis, an observation that is consistent with a pro-survival role for this kinase.

The steric hindrance resulting from a pending 2-fluorobenzyl moiety of the ligand might be the key factor for its ability to overcome cisplatin resistant cancer cells.