Nevertheless, various studies proposed that ASCs can overcome this lineage commitment and differentiate into renal epithelia.
She got married in 1929, and wrote two more novels: "The Chinaberry Tree: A Novel of American Life" (1931), about a woman who tries to overcome her unimpressive lineage by marrying someone of a higher status, and "Comedy: American Style" (1933), which tackles the pervasiveness of colorism within the black community.
As argued elsewhere on population genetic grounds (Lynch 1996), and given the high degree of structural conservation of the mitoribosomal core shown here, it is unlikely that this destabilization can be overcome by novel (lineage-specific) compensatory base pairs.
MLP incorporation into milk may have evolved in order to succeed in nipple-less milk delivery, which was overcome in the therian lineage by the evolution of nipples as a more sophisticated mode of milk delivery during the passage to viviparity, which is estimated to have occurred about 166 220 Ma (Lefèvre, Sharp, et al. 2010).
Voigt and Wöstemeyer [ 33] used logdet methods to overcome biases resulting from lineage-specific variation in nucleotide composition to estimate distances.
However, how stem cells adapt to a hostile environment, such as the postinfarct myocardium, and whether they efficiently differentiate after engraftment toward the CM lineage, overcoming survival stresses, is not known.
The combination of multiple independent loci, as implemented by the AFLP technique, is expected to overcome the problem of idiosyncratic lineage sorting at individual loci [ 22- 24].
We demonstrated that, even in the presence of incomplete lineage sorting, inclusion of a relatively large number of retroposons can overcome the uncertainty introduced by incomplete lineage sorting (Doronina et al. 2015).
In contrast, members of these GH families have multiplied and diversified in the chrysomelids and curculionid lineages, suggesting that coleopterans have undergone lineage specific adaptations to overcome challenges associated with different feeding regimes.
During reprogramming or direct lineage conversion, the cells need to overcome the epigenetic hierarchy or the barriers between the lineages.
