Sentence examples for overcome delivery from inspiring English sources

The design of non-viral gene vectors with the ability to overcome delivery obstacles is currently under extensive investigation.

In a reverse of conventional Internet wisdom, traditional brick-and-mortar, state-owned enterprises that boast an established distribution system and a valuable customer base may have an edge over brash new Net companies struggling to overcome delivery problems and increase online traffic.

With both these hurdles overcome, delivery of the first machines to roll off the production line is set to commence.

Due to the mannose mediated endocytosis and the favorable effects of PS in overcoming delivery barriers, MCMC/PS/CaCO3/ODN nanoparticles exhibit a much higher ODN delivery efficiency and a significantly enhanced immune stimulation capacity as compared with Lipofectamine 2000/ODN complexes.

Gene delivery strategies to overcome these delivery issues have been devised [ 188- 193], with a phase I clinical study having been completed for the treatment of RA [ 194, 195] and an ongoing study for the treatment of OA [ 196].

In this review, we provide insights into the development of non-viral synthetic miRNA vectors and the promise of miRNA-based anticancer therapies, including therapeutic applications of miRNAs, challenges of vector design to overcome the delivery obstacles, and the development of miRNA delivery systems for cancer therapy.

Liposomes have been used as a method to overcome some delivery issues and, in combination with hyperthermia, have been shown to increase drug delivery to tumors.

This review highlights the barriers restricting delivery to the connective tissue interstitium, lymphatics, and lymph nodes as well as advances in engineering drug carriers to overcome these delivery challenges.

Recent progress establishes that gene transfer can now likely overcome the delivery issues plaguing the translation of neurotrophic factors.

The primary focus needs to be to overcome the "delivery deficit" that is a drain not just on popular support for the E.U., but on opportunity and security for our populations.

Through evaluating the recent reported studies in this field, we introduce the progress in designing targeted nano-scaled strategies that are anticipated to overcome the delivery drawbacks and along with the exciting "omics" discipline to personalize RNAi-based therapeutics.