Sentence examples for overcome cells from inspiring English sources
Finally, in addition to promoting the sensitivity of a small-molecule inhibitor of the mitotic kinesin Eg5, SIK3 depletion was able to overcome cells that developed drug resistance.
However, a long follow-up is required before concluding that these strategies will overcome cell resistance.
Combining efforts to overcome cell turnover together with appropriate animal models will enable the field to make continued progress and to reach the step into the clinic.
To overcome cell death caused by reaction products from in situ polymerization, we encapsulated bone marrow-derived stem cells (BMSCs) in fastdegrading, oxidized alginate beads prior to mixing with the hydrophobic precursors.
The purpose of this study was to produce small and narrow-sized cationic nanoparticles able to overcome cell membranes and improve the biological activity of benznidazole (BNZ) in normal and cancer cells.
The shortcomings of current therapeutic modalities are highlighted and a broad spectrum strategy using approaches including (a) gossypol; (b) epigallocatechin-3-gallate; (c) UMI-77 (d) triptolide and (e) selinexor that can be used to overcome cell death resistance is presented.
The rationale for HDCT is that escalating doses of HDCT may increase survival by capturing putatively remnant malignant cells and thus overcome cell resistance to standard chemotherapy [7].
The up-regulation of genes encoding proteins of cell wall biosynthesis may help the organism to overcome cell surface-damaging components present in BALF.
Attempts to overcome cell-cycle dependent resistance have included administration of drugs to preferentially disturb the regulation of the cell-cycle and DNA-repair in cancers compared to the cells of normal tissues [5], [6], [7].
Consistently, IL-2 and other IL-2Rγ-chain binding cytokines, such as IL-7, were able to overcome cell death [18], and, in earlier reports, have been shown to interfere with both murine and human Treg-mediated suppression [17], [20].
The level increases for choline, PC and GPC and the decrease of glycerol were probably to overcome cell membrane damages.
