Sentence examples for overcome cap from inspiring English sources

Combination of a dual PI3K/Akt/mTOR pathway inhibitor (BEZ235) with RT can overcome CaP radioresistance and holds promise for future CaP treatment.

Our recent report also indicated that the downregulation of CD44 using small interfering RNA (siRNA) enhances radiosensitivity in CaP cells, further confirming that targeting CSCs may overcome CaP radioresistance and prevent recurrence after RT.

Although three-dimensional conformal RT, intensity-modulated radiation therapy and image guided radiation therapy can increase the dose to local CaP and improve control rate, the clinical outcomes indicate that these advanced approaches cannot completely overcome radioresistance in CaP.

To overcome this problem, CAP in a micronized form was used and proven to have virucidal activity against HIV-1 IIIB [ 31] and shown to be effective in reducing vaginal infection by simian immunodeficiency virus (SIV) in a macaque model [ 34].

These results indicate that BEZ235 can greatly improve radiosensitivity and overcome radioresistance in CaP-RR cells through inhibiting the PI3K/Akt/mTOR signaling pathway associated with the downregulation of EMT/CSC expression.

Our results further indicate that both CD147 and CD44v3-10 may be potential therapeutic targets for treating late-stage, incurable, recurrent metastatic CaP to overcome drug resistance.

The findings from this study suggest that the combination of dual PI3K/Akt/mTOR inhibitors (BEZ235 or PI103) with radiotherapy is a promising modality for the treatment of CaP to overcome radioresistance.

Fourier-Transform Infrared (FTIR) analysis revealed the hydrolysis of CAP which was overcome by EDC [1-ethyl-3- 3-dimethylaminopropyl) carbodiimide] and EDC/NHS (N-hydroxysuccinimide) cross-linking resulting in its stability (pH of 7.2) for three months.

Given that CD147 and CD44v3-10 colocalise with MDR1-positive cells in CaP specimens, their targeting could potentially overcome drug resistance in the late stage of metastatic CaP.

But the Magic has enough cap space ($8.2 million) to overcome the "poison pill" nature of the young center's contract.

Ten England caps to date but must overcome England's curious resistance to leg-spin.