Sentence examples for overcome a defect from inspiring English sources
Similar to the VscC2 protein, vector-expressed vtrB could overcome a defect in VPA1343 production in vtrA deletion strains, such as WTΔvtrA and WTΔvtrAΔvtrB, whereas vector-expressed vtrA did not induce VPA1343 production in vtrB deletion strains (WTΔvtrB and WTΔvtrAΔvtrB) (Fig. 2D, lower panel).
Synthetic lethality might be compromised because cancers may employ multiple pathways to overcome a defect in one DNA repair pathway [31].
Our results demonstrate that potential alternative pathways for proline synthesis or inter-generation transfer of proline are not sufficient to overcome a defect in proline biosynthesis from glutamate during pollen development.
The magnitude of this allosteric activation may be sufficient to overcome a partial biochemical defect; but not in cases where the residual amount of enzyme is too low.
To assess whether by using VSV-G-pseudotyped HIV-1 vectors we were overcoming an entry defect in Jurkat knockdown clones, similar experiments were performed with a gp120-pseudotyped lentiviral vector.
However, this ectopic expression would not be able to overcome any defect associated with loss of HP1E retention of particular loci in paternal chromatin.
To overcome this defect a direct method of estimating the advance in stand development due to Type 1 responses is suggested.
This treatment is able to overcome the defect that a single infusion cannot offer a sufficient or effective number of cells to eradicate tumor cells.
However, in this latter case, modulation of additional genes involved in energy metabolism, such as ENO1 is consistent with our metabolomics findings, showing a reduced aerobic glycolysis and an increased proteolysis to overcome this defect and produce the required ATP.
To overcome this defect, we developed an improved bistable energy harvester (IBEH) from BEH by adding a small magnet at the middle of two fixed magnets.
Sar1A is in fact expressed at high level in calvarial osteoblasts but evidently not a sufficient level to overcome the defect arising from F382L mutation in Sec23A (Fromme et al. 2007).
