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We combined the effect estimates and standard errors from the community-specific Poisson regression models using random-effects meta-analysis to obtain an overall effect across the study domain (Berkey et al. 1998).
Thus, in the continuum of explanatory or pragmatic trial designs, the overall balance of study domains places this study towards the pragmatic side and will allow more direct application of the information and help decision makers choose whether to implement the interventions tested in the trial.
Results show that the 11-year overall mean of predicted PM2.5 was 67.1 μg/m3 in our study domain.
Our assessment of the correlations between the MMSE domains and the corresponding neuropsychological tests should be taken within context of overall study findings, and not as a recommendation to only administer specific domains of the MMSE.
The overall study quality is considered to be strong if none of the quality domains is rated as weak, moderate if one domain is rated as weak, and weak if two or more domains are rated as weak.
When at least four domains had a low risk score, with at least one of the domains needing to be sequence generation or allocation concealment, we considered the overall study quality to be high.
conceived the overall study.
K.S. conducted overall study design.
directed the overall study design.
S.J.C. conceived and coordinated the overall study.
W.I.C and L.A.A supervised the overall study.
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CEO of Professional Science Editing for Scientists @ prosciediting.com