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Part of the overall silence may be the Tea Party effect.
— but overall "Silence!" feels like a by-the-numbers gag musical that doesn't just fail to break any new ground but also covers its familiar territory with only sporadic flashes of ingenuity.
But as for my friends who identify as conservatives: overall silence.
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Despite overall silencing of integrated retroviral and lentivector promoters during hiPSC generation, low level expression of viral transgenes or vector promoters has the potential for insertional mutagenesis or malignant transformation following cardiac differentiation [23].
Any form of repeated T-DNA arrangement appears to increase the overall silencing probability [ 28, 92].
Overall, silencing of ZNF genes represented a substantial portion (12 of 46, ~26%) of all the significantly downregulated genes in CAsE-PE that were correlated with increased DNA methylation.
The additive enhancement of reactivation by combinatorial knockdown is likely due to hypomorphic effect of individual siRNA knockdowns that, when superimposed, reduce the overall silencing contribution of the Mbd1-Atf7ip-Setdb1 arm in the XCI pathway, or may indicate additional functions of these proteins outside of the DNA/H3K9 methylation axis.
If fanatical Muslims obtain more power, they might seek revenge from the overall Christian silence and peaceful stand in the country.
To provide additional evidence for overall transcriptional silencing of the XY body, at least in part of the pachytene nuclei, we performed an RNA-FISH experiment to detect nascent transcripts containing repeats.
Another possibility is that exogenously delivered miRNA compete with endogenous miRNA for RISC association and cause some distortion of the overall gene silencing profile by repressing the function of endogenous miRNA.
They create so much fear, and they are so directed against anything that is progressive – the right to an education, the rights of unions, the rights of working people – I see, are all part of an overall attack to silence the majority of people and create the kind of climate of fear that allows for us to move very, very sharply to the right.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com