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There was no difference in lenvatinib exposure between the Japanese and overall SELECT populations after adjusting for body weight.
In Japanese patients with radioiodine‐refractory differentiated thyroid cancer, lenvatinib showed similar clinical outcomes to the overall SELECT population.
Japanese patients were similar to the overall SELECT population in terms of age and baseline Eastern Cooperative Oncology Group performance status.
Overall, select genes belonging to extracellular matrix and its remodeling, inflammation, cytoskeleton and migration, and growth factor signaling were found to be affected by FGF2.
The safety profile of lenvatinib among patients from Japan was also similar to that observed in the overall SELECT study population, with a few notable differences in the incidences of several AEs.
17, 24 We investigated whether the difference in body weight between Japanese patients and the overall SELECT study population resulted in differences in exposure to lenvatinib, and therefore could possibly explain the observed differences in safety profile.
Similar(51)
Overall, selecting the most efficient and promising pattern was left to economic analysis.
Sixteen images for each CT protocol modality were overall selected and randomly arranged over the stack of 543 images.
However, if we apply APQ after the LS pairing, we would expect that the overall selected pairwise features are located farther away from the origin.
Overall, selected micropollutants in both lists are structurally diverse, have wide-ranging physico-chemical properties and cover a large spectrum of applications.
Virginia Tech had a record nine players selected in the draft, with Darryl Tapp (31st overall) selected first from the Hokies.
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