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The overall perforation rate was 20% (6/30) among the Albanian-name patients and 16.7% (20/120) in the Greek-name patients.
The overall perforation ratio was 26.54% in the LIP patients, which was similar to the value of 26.01% in the NP patients.
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Two of the 4 DLTs observed overall were gastrointestinal perforations.
While we can be confident that the overall rates of TM perforation are extremely high in this population (95%CI 19 to 29%), it is more difficult to predict the perforation prevalence for other individual communities.
Sakkas et al. reported no impact of membrane perforation on the overall implant within a 1-year evaluation [12], whereas Proussaefs et al. reported a decreased implant survival in two-stage procedures and membrane tear compared to intact membranes (69.56 vs. 100%) [10], as did a study published by Khoury [7].
Abdominoperineal resections are associated with increased CRM involvement, increased intraoperative tumour perforations and decreased overall survival (Marr et al, 2005; Nagtegaal et al, 2005).
Of note, performing physicians must be particularly vigilant of colonic perforation, which has an overall incidence of 4% and carries a 10% mortality rate.
They reported an overall complication rate of 34% and a screw perforation rate of 25%, with a primary screw perforation rate of 14% as well as a secondary perforation rate of 11%.
The surgical management in cases of a membrane perforation might also influence the overall postoperative outcome and complications.
Complications related to AEN included strictures (10.2%), mediastinitis/abscess (5.7%), and perforation (6.8%), and the overall mortality rate was 31.8% [1].
The complete en bloc resection rate was 95.1%, perforation rate was 0.5%, and overall post-operative bleeding rate was 4.7%.
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