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This hybrid homology model was subjected to protein preparation wizard for H-bond optimization, heterogeneous state generation, protonation and overall minimization.
Crystal structure was subjected to protein preparation wizard for filling missing loops and side chains (using prime), ionization, H-bond optimization, heterogeneous state generation, protonation and overall minimization.
For Cdk2 docking, the Cdk2 apoprotein (PDB ID: 1FIN) was subjected to protein preparation wizard for filling missing loops and side chains (using prime), ionization, H-bond optimization, heterogeneous state generation, protonation and overall minimization.
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Various objective functions were considered, including maximization of permeate throughput (overall recovery), minimization of energy consumption, and minimization of boron concentration in permeate.
Therefore, empty containers handling cost also does not impact the overall cost minimization process.
Therefore, cld r is invariable for the whole system and can be omitted from the overall cost minimization process.
Numerical results illustrate the convergence properties of the proposed algorithms and their performance in terms of overall power minimization in the network.
Iltis et al. [23] formulate the problem as a non-cooperative game for overall power minimization of the network under a constant QoS constraint (i.e., target signal-to-interference plus noise ratio (SINR)).
Briefly, the protein structures were curated using the Schrodinger Suite's Protein Preparation Wizard [55, 57] where missing side chains were generated using PRIME [58 60], tautomeric states generated with EPIK [61 63], and an overall energy minimization was performed with the OPLS3 force field [64].
Local services should therefore be alerted to the need for routine monitoring of adherence to AHT, because this is a key performance indicator for both management of hypertensive patients and overall cost minimization in CVD.
With an equally divided time allocation, i.e., t s =T p =0.5 ms, one scheme is derived from the overall average power minimization problem.
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